by admin | Jun 24, 2024 | reserach
(A) roGFP2 contains two Cys residues capable of forming an intramolecular disulfide bond in response to changes in intracellular EGSH. The redox equilibrium of roGFP2 with the GSH/GSSG couple occurs through endogenous glutaredoxins and proceeds slowly. (B) Fusion of...
by admin | Jun 24, 2024 | reserach
Moxifloxacin-mediated killing of M. tuberculosis involves accumulation of NADH-dependent ROS, which is further enhanced by NAC. (A) Moxifloxacin enters M. tuberculosis and traps gyrase on DNA as reversible, bacteriostatic drug-enzyme-DNA complexes in which the DNA is...
by admin | Jun 24, 2024 | reserach
Transmission electron microscopic (TEM) analysis ofMtbnucleoids. TEM images of the longitudinal and transverse sections of: (A, B) wt Mtb from mid-log phase culture showing a well spread out nucleoid in the middle of the cell; (C, D)whiB4-OE cells showing highly...
by admin | Apr 19, 2024 | News and Updates
He is a Professor in the Department of Microbiology and Cell Biology (MCB), and the Centre for Infectious Disease Research (CIDR). Prof Singh has made outstanding contributions to our fundamental understanding of host-pathogen interactions underlying infections caused...
