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Viral Biosafety Level – 3 (Viral BSL-3) Laboratory

The Viral Biosafety level three facility (BSL-3) has been established in the Centre for Infectious Disease Research (CIDR) Building, IISc Campus, Bangalore for conducting research on BSL3 category viral pathogens such as SARS-CoV-2. It consists of one BSL3 lab for cell-based experiments and one infection-cum-necropsy room for animal experiments. There are appropriate change rooms, an autoclave room, and a plant room. This lab has special safety and engineering features for maintaining requisite negative pressure environment to ensure unidirectional airflow, and for ensuring safety of lab personnel. Go through the SOPs to understand the prerequisites for accessing the facility.

We undertake consultancy research projects​ related to vaccine or anti-viral studies. For further details contact at shashankt@iisc.ac.in

VACCINE STUDIES

GENNOVA BIOPHARMACEUTICALS LTD., INDIA

Evaluating efficacy of a mRNA based Covid-19 vaccine candidate (GEMCOVAC-19)​

GLYCOVAX PHARMA, CANADA

Evaluating efficacy of a glycoconjugate vaccine candidate against SARS-CoV-2 ​

PREMAS BIOTECH PVT LTD. INDIA

Evaluating efficacy of a Virus like particle vaccine candidate against SARS-CoV-2​

CSIR-IMTECH, INDIA

To test efficacy of a subunit vaccine against SARS-CoV-2 virus​

CSIR-CCMB . Hyderabad

Evaluating efficacy of a mRNA based Covid-19 vaccine candidate​

BABA ATOMIC RESEARCH CENTRE, MUMBAI, INDIA

Evaluating efficacy of a Liposomal Spike vaccine candidate against SARS-CoV-2

ANTIVIRAL STUDIES

GENEXT GENOMICS PVT LTD

Evaluating efficacy of an anti-SARS-CoV-2 ScFVs in Spike pseudotyped entry assay​

BIOMONETA RESEARCH PVT. LTD., INDIA

Evaluating the efficacy of ZeBox in eliminating airborne influenza and SARS-CoV-2 viruses.​

KASHIV BIOSCIENCES, USA

To test in vitro antiviral efficacy of new synthetic chemical entities against SARS-CoV-2 in cell culture system​

SHARP BUSINESS SYSTEMS, INDIA

To test for the in vitro anti SARS-CoV-2 activity of TUNGSTEN TRIOXIDE-COATED PLATES and NATURIZER (disinfectant) solution​

CSIR-CIMAP, INDIA

To test the anti-SARS-CoV-2 activity of different herbal formulations through oral administration.

SERVICES PROVIDED

RT-PCR related assays

SARS-CoV-2 Viral load, pro- and anti-inflammatory cytokine levels.​

ELISA-based assays

SARS-CoV-2 RBD-specific antibodies and cytokine levels.​

Histology Studies

Lungs, spleen, liver, nasal turbinates, etc.​

Neutralization assays

Live virus and Pseudovirus-based assays​

Small-animal studies

Mice and hamsters to monitor body weight, clinical signs, and organ gross morphology.​

Cytotoxicity and antiviral assays

In multiple cell lines and organoid models​

Dr. Shashank Tripathi
Faculty Incharge
VIRAL Biosafety Level-3 Laboratory
Centre for Infectious Disease Research (CIDR)
MCB Department
Indian Institute of Science
CV Raman Avenue
Bangalore-560012
India
080-2292884/3063

Dr. Rohan Narayan
Incharge
VIRAL Biosafety Level-3 Laboratory
Centre for Infectious Disease Research (CIDR)
Indian Institute of Science
CV Raman Avenue
Bangalore-560012
India
080-2292884/3063